Research is not just finding the finance, fulfilling the Awarded Master/ Doctor or promoting the designation as senior lecturer, associate professor or professor. Research is about good will, drops of blood and tears to find out the new things that improve, repair and develop the quality of life. No matter what shall you get, the most importance is what you contribute……
Elective is one of subject offered by Diploma of Pharmacy Program, Universiti Kuala Lumpur, Royal College of Medicine Perak. Even the name is elective but this course is compulsory to be taken by student. This subject is aimed to stimulate an interesting of student in research activity. Elective was chosen as a title since student has an authority to take the research area in which they interest and curious to investigate.
The area of research is categorized as Pharmacoterapy, Health Development, Instrumentation, Pharmacy Marketing, and Alternative & Traditional Medicines. Various topics have been chosen and run by students and they work in a group. So far, the most area that has been favorable by students is Health Development. This type of research is a public survey and various topics such as alcoholic behavior, people knowledge about breast cancer, obesity and so on was run already. On the other hands, a few students have chosen a laboratory experiment that is categorized as Alternative & Traditional Medicines. The topics are sort of antimicrobial activity of herbal product and determination of vitamin C in fruits was conducted to trigger the interesting of students in pharmacy laboratory.
Currently, a new genre of research area has been created by group which was named as GENESIS. This group is formed by Semester 4 students,June 2008 intake, which consist of 6 members, i.e. Ooi Ah Guan, Mark Tihdnoe Joel, Loa Wei Jyh, Loe Qiau Wei, Song Mei Lai and Serene Sung Su Yin. The present area is Drug Discovery that is focused on Drug Synthesis.
Currently, a new genre of research area has been created by group which was named as GENESIS. This group is formed by Semester 4 students,…..intake which consist of 6 members, i.e. Ooi Ah Guan, Mark Tihdnoe Joel, Loa Wei Jyh, Loe Qiau Wei, Song Mei Lai and Serene Sung Su Yin. The present area is Drug Discovery that is focused on Drug Synthesis.
The topic is about synthesis of benzylidene ketone derivatives. Based on the previous studies, this chemical derivative has been established as anti-inflammatory, anticancer, antioxidant, antimicrobial, and so many pharmacological activities. They aim to develop another analogue that is predicted has the similar bioactivity with the previous compounds.
The molecule target at which they want to produce is 2,4-bis-(4-nitrobenzylidene)-3-pentanone. This product can be synthesized by reacting 4-nitrobenzaldehyde and 3-pentanone as a starting material in ethanol as a solvent and use sodium hydroxide as a catalyst. The physical properties were analyzed by using macroscopic and solubility test. The purity of product was tested by Thin Layer Chromatography (TLC), and the molecule structure was elucidated by using Ultraviolet-Visible (UV-Vis) Spectroscopy.
So far, the result of analysis shows the physico-chemical properties that are close to the predicted molecule target. To establish its exact molecule structure, the sequence of structure elucidation such as Infrared (IR), Nuclear Magnetic Resonance (NMR) and Liquid Chromatography-Mass spectroscopy (LC-MS) has been running for now.
Hopefully, this research can stimulate the UniKL-RCMP societies, Pharmacy especially, in Laboratory atmosphere. No Laboratory-No Pharmacy. There are still so many problems in disease treatment such as cancer and viral disease that needs so many contributions of pharmacy and related discipline to find the solution, and off course the DRUG DISCOVERY is highly needed in this term. To GENESIS, you’ve done the best all you ever had, CONGRATULATION!!! So, DRUG DISCOVERY in UniKL-RCMP?? Why not???